BDBM50024354 CHEMBL3330444::US10106557, Compound 2

SMILES [H][C@@]12COc3cc(ccc3N1C(=O)O[C@H]2CNC(=O)c1ccc(Cl)s1)N1CCCCC1=O

InChI Key InChIKey=JCTRHKZXDDIGIB-HOCLYGCPSA-N

Data  5 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50024354   

TargetSerine protease 1(Homo sapiens (Human))
North China Pharmaceutical New Drug R&D

US Patent
LigandPNGBDBM50024354(CHEMBL3330444 | US10106557, Compound 2)
Affinity DataKi: >2.00E+4nMpH: 8.2Assay Description:The inhibitory activity on human trypsin was determined by using buffer (50 mM Tris, pH 8.2, and 20 mM CaCl2). Appropriate wells in the Greiner 384 m...More data for this Ligand-Target Pair
In DepthDetails US Patent