BDBM50464867 CHEMBL4289783

SMILES Fc1ccc(N2CCN(CCCc3c[nH]c4ccc(F)cc34)CC2)c(c1)-c1ccccc1

InChI Key InChIKey=GPVZPQVIHIFYGO-UHFFFAOYSA-N

Data  4 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50464867   

TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Shanghai Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50464867(CHEMBL4289783)
Affinity DataIC50:  25nMAssay Description:Inhibition of [3H]serotonin reuptake in rat brain synaptosomes SERT after 15 mins by TopCount scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Shanghai Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50464867(CHEMBL4289783)
Affinity DataIC50:  177nMAssay Description:Inhibition of serotonin transporter in rat brain tissue assessed as inhibition of [3H]-5-hydroxytryptamine reuptakeMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed