BDBM21492 4-[3-(pyridin-2-yl)-1H-pyrazol-4-yl]quinoline::CHEMBL261454::LY364947::US11759530, Compound Table1.1::US9138393, LY-364947::US9144538, LY-364947
SMILES c1[nH]nc(c1-c1ccnc2ccccc12)-c1ccccn1
InChI Key InChIKey=IBCXZJCWDGCXQT-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 11 hits for monomerid = 21492
Affinity DataKd: 5nMAssay Description:Dissociation constant for TGF-beta receptor type IMore data for this Ligand-Target Pair
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of Transforming growth factor beta-1 receptor (TbetaRI) autophosphorylationMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of TGFbeta R1 induced transcriptional activation of p3TP-Lux in mink Mv1Lu lung cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 47nMAssay Description:In vitro inhibition of transforming growth factor- beta dependent luciferase production in mink lung cells (p3TP Lux)More data for this Ligand-Target Pair
Affinity DataIC50: 740nMAssay Description:In vitro inhibitory activity against Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
Affinity DataIC50: 51nMAssay Description:Inhibition of human Transforming growth factor (TGF) beta-1 receptor (T204D mutation) autophosphorylation in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 89nMAssay Description:In vitro inhibition of transforming growth factor- beta dependent luciferase growth in mouse fibroblasts (NIH 3T3)More data for this Ligand-Target Pair
Affinity DataIC50: 59nMAssay Description:Inhibition of recombinant human TGFbeta R1 expressed in Sf9 cellsMore data for this Ligand-Target Pair