BDBM50599241 CHEMBL5198162::US11884671, Example 43

SMILES CN1CCC(CC1)n1c2nc(Nc3cc4ccnnc4cc3C)ncc2n(C)c1=O

InChI Key InChIKey=IWUSAMFKHBZSJS-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50599241   

TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM50599241(CHEMBL5198162 | US11884671, Example 43)
Affinity DataIC50: >1.00E+4nMAssay Description:JAK1: The 2×JAK/Tyr 06 (ThermoFisher Scientific proprietary) mixture was prepared in 50 mM HEPES pH 6.5, 0.01% BRIJ-35, 10 mM MgCl2, 1 mM EGTA, 0.02%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent