BDBM127657 US10251889, Example 30::US10758542, Example 30::US8791123, 30::US9782415, Example 30::US9796724, Example 30

SMILES NC(=O)c1cnn2ccc(nc12)N1CCC[C@@H]1c1cc(F)ccc1F

InChI Key InChIKey=JBTQGTQNCVBRNY-CQSZACIVSA-N

Data  32 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 127657   

TargetTyrosine-protein kinase JAK1 [866-1154](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM127657(US10251889, Example 30 | US10758542, Example 30 | ...)
Affinity DataIC50: >1.00E+3nMAssay Description:Compounds of Formula I were screened for their ability to inhibit Jak1 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1 [866-1154](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM127657(US10251889, Example 30 | US10758542, Example 30 | ...)
Affinity DataIC50: >1.00E+3nMAssay Description:Jak1: Compounds of Formula I were screened for their ability to inhibit Jak1 using the general enzyme inhibition assay method, in which the assay mix...More data for this Ligand-Target Pair
In DepthDetails US Patent