BDBM50527406 CHEMBL4588333::US10981911, Example 45
SMILES Fc1ccc(CNC(=O)Cc2nc3cnc4[nH]ccc4c3n2[C@H]2CC[C@H](CC#N)CC2)cc1
InChI Key InChIKey=MMAFBZVPAFVVFX-RUCARUNLSA-N
Data 9 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 50527406
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Janssen Research and Development
Curated by ChEMBL
Janssen Research and Development
Curated by ChEMBL
Affinity DataIC50: 174nMAssay Description:Inhibition of JAK3-JH1/JH2 domain (512 to 1124 residues) (unknown origin) pre-incubated before NH2-KGGEEEEYFELVKK-CO2 substrate addition and measured...More data for this Ligand-Target Pair