BDBM50015447 CHEMBL3265031
SMILES CC1(O)CCN(CC1)c1ccc(Nc2nc(cn3ccnc23)-c2ccc3cn[nH]c3c2)cc1
InChI Key InChIKey=DOVPFYVNKOVWHA-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50015447
Affinity DataIC50: 1.40nMAssay Description:Inhibition of full length Syk (unknown origin) using biotinylated peptide substrateMore data for this Ligand-Target Pair
Affinity DataEC50: 677nMAssay Description:Inhibition of Syk in goat antihuman IgE-induced CD63 expression in human whole blood by FACS analysisMore data for this Ligand-Target Pair
Affinity DataEC50: 15nMAssay Description:Inhibition of Syk in antihuman IgM-stimulated human Ramos cells assessed as decrease in BCR-mediated BLNK phosphorylation by cellular assayMore data for this Ligand-Target Pair