BDBM373525 US10421747, Compound 7::US9902714, Compound 7

SMILES CCn1cc(cn1)-c1cnc2ccc(cc2n1)N1CCN(Cc2c(OC)cc(OC)cc12)C(C)C

InChI Key InChIKey=IRPMVZSWQAOIAN-UHFFFAOYSA-N

Data  10 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 373525   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM373525(US10421747, Compound 7 | US9902714, Compound 7)
Affinity DataKd:  1.70E+3nMAssay Description:Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan® technologyMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM373525(US10421747, Compound 7 | US9902714, Compound 7)
Affinity DataKd:  1.70E+3nMAssay Description:KDR (VEGFR2): In a final reaction volume of 30 μL, KDR (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent