BDBM373525 US10421747, Compound 7::US9902714, Compound 7
SMILES CCn1cc(cn1)-c1cnc2ccc(cc2n1)N1CCN(Cc2c(OC)cc(OC)cc12)C(C)C
InChI Key InChIKey=IRPMVZSWQAOIAN-UHFFFAOYSA-N
Data 10 Kd
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 373525
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Astex Therapeutics
US Patent
Astex Therapeutics
US Patent
Affinity DataKd: 1.70E+3nMAssay Description:Kinase enzyme binding affinities of compounds disclosed herein were determined using the KINOMEscan® technologyMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Astex Therapeutics
US Patent
Astex Therapeutics
US Patent
Affinity DataKd: 1.70E+3nMAssay Description:KDR (VEGFR2): In a final reaction volume of 30 μL, KDR (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO...More data for this Ligand-Target Pair