BDBM4814 CHEMBL535::N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide::N-[2-(diethylamino)ethyl]-5-{[(3Z)-5-fluoro-2-oxo-2,3-dihydro-1H-indol-3-ylidene]methyl}-2,4-dimethyl-1H-pyrrole-3-carboxamide::SU11248::SUNITINIB::SUNITINIB MALATE::US10464902, Sunitinib::US20240058459, Compound Sunit-inib::US9163010, Sunitinib::US9914707, SU11248
SMILES CCN(CC)CCNC(=O)c1c(C)[nH]c(\C=C2/C(=O)Nc3ccc(F)cc23)c1C
InChI Key InChIKey=WINHZLLDWRZWRT-ATVHPVEESA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 4814
Affinity DataKi: 17nMAssay Description:Binding affinity to VEGFR3 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKd: 50nMpH: 7.4 T: 25°CAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 35nMAssay Description:Average Binding Constant for FLT4; NA=Not Active at 10 uMMore data for this Ligand-Target Pair
Affinity DataKd: 50nMAssay Description:Binding affinity to FLT4More data for this Ligand-Target Pair
Affinity DataKd: 50nMAssay Description:Binding constant for FLT4 kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 50nMAssay Description:Binding constant for FLT4 kinase domainMore data for this Ligand-Target Pair
Affinity DataIC50: 8.90nMAssay Description:Inhibition of VEGFR3More data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Inhibition of human recombinant GST-fused VEGFR3 kinase domain transphosphorylation expressed in baculovirus expression system using poly-Glu-Tyr (4:...More data for this Ligand-Target Pair