BDBM14384 3-(3-Cyclopentyloxy-4-methoxy-benzyl)-8-[1-(4-trifluoromethyl-benzyloxy)-1-methyl-ethyl]-3H-purin-6-ylamine::3-{[3-(cyclopentyloxy)-4-methoxyphenyl]methyl}-8-(2-{[4-(trifluoromethyl)phenyl]methoxy}propan-2-yl)-3H-purin-6-amine::V11294 Analogue 5t
SMILES COc1ccc(Cn2cnc(N)c3nc(nc23)C(C)(C)OCc2ccc(cc2)C(F)(F)F)cc1OC1CCCC1
InChI Key InChIKey=XUANVLMFEXVBQF-UHFFFAOYSA-N
Data 5 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 14384
Affinity DataKi: 309nM ΔG°: -8.79kcal/molepH: 8.0 T: 22°CAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair