BDBM195608 CPI-455

SMILES CC(C)c1c([nH]c2c(cnn2c1=O)C#N)-c1ccccc1

InChI Key InChIKey=DHXKRMSKXLDZGY-UHFFFAOYSA-N

Data  40 IC50  2 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 195608   

TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Genentech

LigandPNGBDBM195608(CPI-455)
Affinity DataEC50:  5.20E+3nMAssay Description:Inhibition of KDM5A in human PC9 cells assessed as increase in H3K4me3 levels preincubated for 4 days measured up to 24 hrs by ELISAMore data for this Ligand-Target Pair
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Genentech

LigandPNGBDBM195608(CPI-455)
Affinity DataEC50:  5.20E+3nMAssay Description:Inhibition of KDM5A in human PC9 cells assessed as increase in H3K4me3 levels preincubated for 4 days measured up to 24 hrs by ELISAMore data for this Ligand-Target Pair