BDBM25118 (3Z)-4-amino-5-fluoro-3-[5-(4-methylpiperazino)-1,3-dihydrobenzimidazol-2-ylidene]carbostyril::4-amino-5-fluoro-3-[6-(4-methylpiperazin-1-yl)-1H-1,3-benzodiazol-2-yl]-1,2-dihydroquinolin-2-one::CHEMBL522892::CHIR-258
SMILES CN1CCN(CC1)c1ccc2nc([nH]c2c1)-c1c(N)c2c(F)cccc2[nH]c1=O
InChI Key InChIKey=PIQCTGMSNWUMAF-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 25118
Affinity DataEC50: 166nMAssay Description:Inhibition of FGFR1 phosphorylation expressed in human KM12L4A cells by Western blot analysisMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Human)
Ambit Biosciences
Curated by PubChem BioAssay
Ambit Biosciences
Curated by PubChem BioAssay
Affinity DataEC50: 51nMAssay Description:Inhibition of PDGFRbeta phosphorylation expressed in human KM12L4A cells Western blot analysisMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Human)
Ambit Biosciences
Curated by PubChem BioAssay
Ambit Biosciences
Curated by PubChem BioAssay
Affinity DataEC50: 46nMAssay Description:Inhibition of human recombinant VEGFR2More data for this Ligand-Target Pair