BDBM454527 US10717746, Example 10

SMILES CC(=O)N[C@@H]1CCC[C@@H](C1)C(=O)Nc1cc(-c2cnn3CCCc23)c(Cl)cn1

InChI Key InChIKey=YFAKZUMJVBULBO-UONOGXRCSA-N

Data  4 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 454527   

TargetCyclin-dependent kinase 9(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM454527(US10717746, Example 10)
Affinity DataEC50:  330nMAssay Description:Inhibition of CDK9 in human MV4-11 cells assessed as induction of caspase-3/7 activation measured after 6 hrs followed by Caspase-glo reagent based a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed