BDBM50237349 CHEMBL4077430

SMILES CN[C@@H]1Cc2cccc3n(CCCCOc4ccc5CCC(=O)Nc5c4)c(=O)n(C1)c23

InChI Key InChIKey=ZJCPSCHGZIVAIV-GOSISDBHSA-N

Data  2 KI  4 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50237349   

TargetD(2) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50237349(CHEMBL4077430)
Affinity DataEC50:  1.50E+3nMAssay Description:Inhibitory constant against trypsin determined in VitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50237349(CHEMBL4077430)
Affinity DataEC50:  255nMAssay Description:Agonist activity at human dopamine D2 receptor expressed in HEK293 cells assessed as cAMP inhibition by BRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50237349(CHEMBL4077430)
Affinity DataEC50:  713nMAssay Description:Agonist activity at human dopamine D2 receptor expressed in HEK293 cells coexpressing renilla luciferase-fused Galphai1/GFP10-fused Ggamma2 by BRET a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50237349(CHEMBL4077430)
Affinity DataEC50:  105nMAssay Description:Inhibitory constant against trypsin determined in VitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed