BDBM358984 (6R,8aS)-6-(8-amino-5- chloro-1-{4-[(1S)-1-(3- cyclopropylphenyl)-1- hydroxyethyl]phenyl} imidazo[1,5-a]pyrazin-3- yl)hexahydroindolizin- 3(2H)-one::US10214546, Example 116
SMILES C[C@](O)(c1ccc(cc1)-c1nc([C@@H]2CC[C@H]3CCC(=O)N3C2)n2c(Cl)cnc(N)c12)c1cccc(c1)C1CC1
InChI Key InChIKey=WCZCYMHMCMIKRL-HKNHFSNESA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 358984
Affinity DataIC50: 0.870nMAssay Description:BTK enzymatic activity was determined with the LANCE (Lanthanide Chelate Excite) TR-FRET (Time-resolved fluorescence resonance energy transfer) assay...More data for this Ligand-Target Pair