BDBM377058 US10259818, Example 40::US9944646, Example 40
SMILES C[C@@H](c1cc(Cl)c(F)c2CN(C[C@H](C)Oc12)S(C)(=O)=O)n1nc(C)c2c(N)ncnc12
InChI Key InChIKey=MFVMQZFCJJWDAY-ONGXEEELSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 377058
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Incyte
US Patent
Incyte
US Patent
Affinity DataIC50: <100nMAssay Description:[γ-33P]ATP (10mCi/mL) was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase substrate, D-myo-Phosphatidylinositol 4,5-bisphosphate (Ptd...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Incyte
US Patent
Incyte
US Patent
Affinity DataIC50: <100nMAssay Description:The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...More data for this Ligand-Target Pair