BDBM50001468 (S)-3-((S)-2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-N-{(S)-1-[(S)-1-(carbamoylmethyl-carbamoyl)-2-methyl-propylcarbamoyl]-2-methyl-propyl}-succinamic acid::3-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-N-{1-[1-(carbamoylmethyl-carbamoyl)-2-methyl-propylcarbamoyl]-2-methyl-propyl}-succinamic acid::CHEMBL317956::H-Tyr-D-Ala-Phe-Asp-Val-Val-Gly-NH2::deltorphin C

SMILES CC(C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(C)C)C(=O)NCC(N)=O

InChI Key InChIKey=CJAORFIPPWIGPG-QXYJMILXSA-N

Data  27 KI  33 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 33 hits for monomerid = 50001468   

TargetDelta-type opioid receptor(Homo sapiens (Human))
Eastern Michigan University

Curated by ChEMBL
LigandPNGBDBM50001468((S)-3-((S)-2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phen...)
Affinity DataIC50:  1.30nMAssay Description:Binding affinity at cloned human delta-opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Astrazeneca R&D Montreal

Curated by ChEMBL
LigandPNGBDBM50001468((S)-3-((S)-2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phen...)
Affinity DataIC50:  225nMAssay Description:Binding affinity at cloned human mu-opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50001468((S)-3-((S)-2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phen...)
Affinity DataIC50:  0.560nMAssay Description:Displacement of [3H]naltrindole from delta opioid receptor in rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50001468((S)-3-((S)-2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phen...)
Affinity DataIC50:  0.170nMAssay Description:Functional bioactivity against delta opioid receptor in mouse vas deferensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Eastern Michigan University

Curated by ChEMBL
LigandPNGBDBM50001468((S)-3-((S)-2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phen...)
Affinity DataIC50:  1.30E+3nMAssay Description:Functional bioactivity against mu opioid receptor in guinea-pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Astrazeneca R&D Montreal

Curated by ChEMBL
LigandPNGBDBM50001468((S)-3-((S)-2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phen...)
Affinity DataIC50:  7.33E+3nMAssay Description:Binding affinity at cloned human opioid receptor kappa 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50001468((S)-3-((S)-2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phen...)
Affinity DataIC50:  0.460nMAssay Description:Inhibitory activity against Opioid receptor delta 1 of mouse vas deferens (MVD)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Eastern Michigan University

Curated by ChEMBL
LigandPNGBDBM50001468((S)-3-((S)-2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phen...)
Affinity DataIC50: >1.50E+3nMAssay Description:Inhibitory concentration against electrically evoked contractions of guinea pig ileum longitudinal muscle-myenteric plexusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50001468((S)-3-((S)-2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phen...)
Affinity DataIC50:  0.730nMAssay Description:Inhibition of [3H]-[p-Cl-Phe-]DPDE binding to rat brain homogenate delta-opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50001468((S)-3-((S)-2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phen...)
Affinity DataIC50:  1.68E+3nMAssay Description:Inhibition of [3H]-CTOP binding to rat brain homogenate mu-opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Eastern Michigan University

Curated by ChEMBL
LigandPNGBDBM50001468((S)-3-((S)-2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phen...)
Affinity DataIC50:  2.89E+3nMAssay Description:In vitro inhibition of electrically evoked contractions in guinea pig ileum longitudinal muscle myenteric plexusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50001468((S)-3-((S)-2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phen...)
Affinity DataIC50:  0.670nMAssay Description:In vitro inhibition of electrically induced smooth muscle contractions of mouse vas deferensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Eastern Michigan University

Curated by ChEMBL
LigandPNGBDBM50001468((S)-3-((S)-2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phen...)
Affinity DataIC50:  854nMAssay Description:Inhibition of electrically evoked contractions in Guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50001468((S)-3-((S)-2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phen...)
Affinity DataIC50:  0.147nMAssay Description:Inhibition of electrically evoked contractions in mouse vas deferensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Eastern Michigan University

Curated by ChEMBL
LigandPNGBDBM50001468((S)-3-((S)-2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phen...)
Affinity DataIC50:  337nMAssay Description:Compound was evaluated for its inhibitory activity towards Opioid receptor mu 1 of guinea pig ileum (GPI)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50001468((S)-3-((S)-2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phen...)
Affinity DataIC50:  0.850nMAssay Description:Agonist activity was evaluated in guinea pig ileum (GPI) preparations at Opioid receptor delta 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Eastern Michigan University

Curated by ChEMBL
LigandPNGBDBM50001468((S)-3-((S)-2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phen...)
Affinity DataIC50:  1.50E+4nMAssay Description:Agonist activity was evaluated in guinea pig ileum (GPI) preparations at Opioid receptor mu 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50001468((S)-3-((S)-2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phen...)
Affinity DataIC50:  0.460nMAssay Description:Functional biological activity for Opioid receptor delta 1 was determined in vitro, on mouse vas deferens (MVD).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Eastern Michigan University

Curated by ChEMBL
LigandPNGBDBM50001468((S)-3-((S)-2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phen...)
Affinity DataIC50:  420nMAssay Description:Functional biological activity for mu opioid receptor was determined in vitro , on guinea pig ileum (GPI).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50001468((S)-3-((S)-2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phen...)
Affinity DataIC50:  0.160nMAssay Description:Inhibitory concentration against delta opioid receptor of electrically induced smooth muscle contraction of mouse vas deferensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50001468((S)-3-((S)-2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phen...)
Affinity DataIC50:  0.730nMAssay Description:Inhibition of [3H]-[p-Cl-Phe-]DPDE binding to rat brain homogenate delta-opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50001468((S)-3-((S)-2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phen...)
Affinity DataIC50:  1.68E+3nMAssay Description:Inhibition of [3H]-CTOP binding to rat brain homogenate mu-opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Eastern Michigan University

Curated by ChEMBL
LigandPNGBDBM50001468((S)-3-((S)-2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phen...)
Affinity DataIC50:  2.89E+3nMAssay Description:In vitro inhibition of electrically evoked contractions in guinea pig ileum longitudinal muscle myenteric plexusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50001468((S)-3-((S)-2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phen...)
Affinity DataIC50:  0.670nMAssay Description:In vitro inhibition of electrically induced smooth muscle contractions of mouse vas deferensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Eastern Michigan University

Curated by ChEMBL
LigandPNGBDBM50001468((S)-3-((S)-2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phen...)
Affinity DataIC50:  420nMAssay Description:Tested for inhibition of amplification of electrically induced twitch in guinea pig ileum (GPI)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(MOUSE)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50001468((S)-3-((S)-2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phen...)
Affinity DataIC50:  0.340nMAssay Description:Tested for inhibition of amplification of electrically induced twitch in mouse vas deferens (MVD)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Eastern Michigan University

Curated by ChEMBL
LigandPNGBDBM50001468((S)-3-((S)-2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phen...)
Affinity DataIC50:  5.44E+3nMAssay Description:In vitro biological activity by electrically induced smooth muscle contractions in guinea pig ileum (Opioid receptor mu 1); inhibitory concentration ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50001468((S)-3-((S)-2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phen...)
Affinity DataIC50:  0.582nMAssay Description:In vitro biological activity by electrically induced smooth muscle contractions in mouse vas deferens (Opioid receptor delta 1); inhibitory concentra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Eastern Michigan University

Curated by ChEMBL
LigandPNGBDBM50001468((S)-3-((S)-2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phen...)
Affinity DataIC50:  2.90nMAssay Description:Inhibitory activity against Guinea pig ileum smooth muscleMore data for this Ligand-Target Pair
In DepthDetails Article
TargetMu-type opioid receptor(Rattus norvegicus (rat))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50001468((S)-3-((S)-2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phen...)
Affinity DataIC50:  2.14E+3nMAssay Description:Binding affinity against Opioid receptor mu 1 with [3H]-CTOPMore data for this Ligand-Target Pair
In DepthDetails Article
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50001468((S)-3-((S)-2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phen...)
Affinity DataIC50:  0.540nMAssay Description:Agonist activity for Opioid receptor delta 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50001468((S)-3-((S)-2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phen...)
Affinity DataIC50:  0.600nMAssay Description:Binding affinity against delta receptor with [3H]-[p-Cl-Phe4]-DPDPEMore data for this Ligand-Target Pair
In DepthDetails Article
TargetDelta-type opioid receptor(MOUSE)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50001468((S)-3-((S)-2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phen...)
Affinity DataIC50:  0.110nMAssay Description:Inhibitory activity against Mouse vas deferens smooth muscleMore data for this Ligand-Target Pair
In DepthDetails Article