BDBM50001468 (S)-3-((S)-2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-N-{(S)-1-[(S)-1-(carbamoylmethyl-carbamoyl)-2-methyl-propylcarbamoyl]-2-methyl-propyl}-succinamic acid::3-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-N-{1-[1-(carbamoylmethyl-carbamoyl)-2-methyl-propylcarbamoyl]-2-methyl-propyl}-succinamic acid::CHEMBL317956::H-Tyr-D-Ala-Phe-Asp-Val-Val-Gly-NH2::deltorphin C
SMILES CC(C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(C)C)C(=O)NCC(N)=O
InChI Key InChIKey=CJAORFIPPWIGPG-QXYJMILXSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 33 hits for monomerid = 50001468
Affinity DataIC50: 1.30nMAssay Description:Binding affinity at cloned human delta-opioid receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 225nMAssay Description:Binding affinity at cloned human mu-opioid receptorMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University
Curated by ChEMBL
Tohoku Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 0.560nMAssay Description:Displacement of [3H]naltrindole from delta opioid receptor in rat brain membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 0.170nMAssay Description:Functional bioactivity against delta opioid receptor in mouse vas deferensMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:Functional bioactivity against mu opioid receptor in guinea-pig ileumMore data for this Ligand-Target Pair
Affinity DataIC50: 7.33E+3nMAssay Description:Binding affinity at cloned human opioid receptor kappa 1More data for this Ligand-Target Pair
Affinity DataIC50: 0.460nMAssay Description:Inhibitory activity against Opioid receptor delta 1 of mouse vas deferens (MVD)More data for this Ligand-Target Pair
Affinity DataIC50: >1.50E+3nMAssay Description:Inhibitory concentration against electrically evoked contractions of guinea pig ileum longitudinal muscle-myenteric plexusMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University
Curated by ChEMBL
Tohoku Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 0.730nMAssay Description:Inhibition of [3H]-[p-Cl-Phe-]DPDE binding to rat brain homogenate delta-opioid receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 1.68E+3nMAssay Description:Inhibition of [3H]-CTOP binding to rat brain homogenate mu-opioid receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 2.89E+3nMAssay Description:In vitro inhibition of electrically evoked contractions in guinea pig ileum longitudinal muscle myenteric plexusMore data for this Ligand-Target Pair
Affinity DataIC50: 0.670nMAssay Description:In vitro inhibition of electrically induced smooth muscle contractions of mouse vas deferensMore data for this Ligand-Target Pair
Affinity DataIC50: 854nMAssay Description:Inhibition of electrically evoked contractions in Guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataIC50: 0.147nMAssay Description:Inhibition of electrically evoked contractions in mouse vas deferensMore data for this Ligand-Target Pair
Affinity DataIC50: 337nMAssay Description:Compound was evaluated for its inhibitory activity towards Opioid receptor mu 1 of guinea pig ileum (GPI)More data for this Ligand-Target Pair
Affinity DataIC50: 0.850nMAssay Description:Agonist activity was evaluated in guinea pig ileum (GPI) preparations at Opioid receptor delta 1More data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+4nMAssay Description:Agonist activity was evaluated in guinea pig ileum (GPI) preparations at Opioid receptor mu 1More data for this Ligand-Target Pair
Affinity DataIC50: 0.460nMAssay Description:Functional biological activity for Opioid receptor delta 1 was determined in vitro, on mouse vas deferens (MVD).More data for this Ligand-Target Pair
Affinity DataIC50: 420nMAssay Description:Functional biological activity for mu opioid receptor was determined in vitro , on guinea pig ileum (GPI).More data for this Ligand-Target Pair
Affinity DataIC50: 0.160nMAssay Description:Inhibitory concentration against delta opioid receptor of electrically induced smooth muscle contraction of mouse vas deferensMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University
Curated by ChEMBL
Tohoku Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 0.730nMAssay Description:Inhibition of [3H]-[p-Cl-Phe-]DPDE binding to rat brain homogenate delta-opioid receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 1.68E+3nMAssay Description:Inhibition of [3H]-CTOP binding to rat brain homogenate mu-opioid receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 2.89E+3nMAssay Description:In vitro inhibition of electrically evoked contractions in guinea pig ileum longitudinal muscle myenteric plexusMore data for this Ligand-Target Pair
Affinity DataIC50: 0.670nMAssay Description:In vitro inhibition of electrically induced smooth muscle contractions of mouse vas deferensMore data for this Ligand-Target Pair
Affinity DataIC50: 420nMAssay Description:Tested for inhibition of amplification of electrically induced twitch in guinea pig ileum (GPI)More data for this Ligand-Target Pair
Affinity DataIC50: 0.340nMAssay Description:Tested for inhibition of amplification of electrically induced twitch in mouse vas deferens (MVD)More data for this Ligand-Target Pair
Affinity DataIC50: 5.44E+3nMAssay Description:In vitro biological activity by electrically induced smooth muscle contractions in guinea pig ileum (Opioid receptor mu 1); inhibitory concentration ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.582nMAssay Description:In vitro biological activity by electrically induced smooth muscle contractions in mouse vas deferens (Opioid receptor delta 1); inhibitory concentra...More data for this Ligand-Target Pair
Affinity DataIC50: 2.90nMAssay Description:Inhibitory activity against Guinea pig ileum smooth muscleMore data for this Ligand-Target Pair
Affinity DataIC50: 2.14E+3nMAssay Description:Binding affinity against Opioid receptor mu 1 with [3H]-CTOPMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University
Curated by ChEMBL
Tohoku Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 0.540nMAssay Description:Agonist activity for Opioid receptor delta 1More data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Tohoku Pharmaceutical University
Curated by ChEMBL
Tohoku Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Binding affinity against delta receptor with [3H]-[p-Cl-Phe4]-DPDPEMore data for this Ligand-Target Pair
Affinity DataIC50: 0.110nMAssay Description:Inhibitory activity against Mouse vas deferens smooth muscleMore data for this Ligand-Target Pair