BDBM50013712 2-aminopyridin::2-aminopyridine::CHEMBL21619::Pyridin-2-ylamine

SMILES c1ccnc(c1)N

InChI Key InChIKey=ICSNLGPSRYBMBD-UHFFFAOYSA-N

Data  1 KI  7 IC50  2 Kd

PDB links: 5 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50013712   

TargetBotulinum neurotoxin type A(Clostridium botulinum)
U.S. Army Medical Research Institute of Infectious Diseases

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50013712BDBM50013712(Pyridin-2-ylamine | 2-aminopyridine | CHEMBL21619 ...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of protease activity of recombinant full length Clostridium botulinum Hall BoNT/A light chain using SNAP-25 peptide (187 to 203 residues) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2019
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50013712BDBM50013712(Pyridin-2-ylamine | 2-aminopyridine | CHEMBL21619 ...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibitory activity against inducible nitric oxide synthase (iNOS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50013712BDBM50013712(Pyridin-2-ylamine | 2-aminopyridine | CHEMBL21619 ...)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibitory activity against endothelial nitric oxide synthase (eNOS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50013712BDBM50013712(Pyridin-2-ylamine | 2-aminopyridine | CHEMBL21619 ...)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibitory activity against neuronal nitric oxide synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhosphatidylinositol 4-kinase type 2-alpha(Human)
Smith Kline & French Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50013712BDBM50013712(Pyridin-2-ylamine | 2-aminopyridine | CHEMBL21619 ...)
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibitory activity (IC50) against human phosphatidylinositol 4-kinase at the ATP binding siteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2019
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50013712BDBM50013712(Pyridin-2-ylamine | 2-aminopyridine | CHEMBL21619 ...)
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibition of human nNOS by hemoglobin capture assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Rat)
Northwestern University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50013712BDBM50013712(Pyridin-2-ylamine | 2-aminopyridine | CHEMBL21619 ...)
Affinity DataIC50: 8.70E+3nMAssay Description:Inhibition of wild type rat nNOS by hemoglobin capture assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed