BDBM50049240 (+-)-5-((4-(2-(5-ethyl-2-pyridinyl)ethoxy)phenyl)methyl)-2,4-thiazolidinedione::5-{4-[2-(5-ethylpyridin-2-yl)ethoxy]benzyl}-1,3-thiazolidine-2,4-dione::CHEMBL595::PIOGLITAZONE::PIOGLITAZONE HYDROCHLORIDE
SMILES CCc1ccc(CCOc2ccc(Cc3sc(=O)[nH]c3O)cc2)nc1
InChI Key InChIKey=IYYGBZJXHJSLEV-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 50049240
Affinity DataIC50: >1.00E+4nMAssay Description:Receptor binding affinity of the compound to human Peroxisome proliferator activated receptor alpha against [3H]-NNC 0061-4655 radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 7.40E+3nMAssay Description:Receptor binding affinity of the compound to human Peroxisome proliferator activated receptor gamma against [3H]-ragalitazar radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:Displacement of [3H]rosiglitazone from PPAR gammaMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Rat)
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
National Institute of Pharmaceutical Education and Research
Curated by ChEMBL
Affinity DataIC50: 700nMAssay Description:Displacement of [3H]rosigliatzone from PPARgamma in rat adipocytesMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Mouse)
Glaxo Wellcome Research & Development
Curated by ChEMBL
Glaxo Wellcome Research & Development
Curated by ChEMBL
Affinity DataIC50: 700nMAssay Description:Displacement of [3H]rosiglitazone from mouse PPARgamma receptor by scintillation proximation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.20E+5nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
Affinity DataIC50: 855nMAssay Description:Displacement of fluormone PPAR-green from N-terminal His-tagged human PPARgamma-LBD after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of fluormone binding to human PPARgamma LBD after 2 hrs by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Francisella tularensis subsp. tularensis (strain S...)
Naval Research Laboratories
Curated by ChEMBL
Naval Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 7.90E+4nMAssay Description:Inhibition of C-terminal His6-tagged Francisella tularensis SCHU S4 FabI expressed in Escherichia coli BL21 (DE3) using CrCoA as substrate assessed a...More data for this Ligand-Target Pair
Affinity DataIC50: 298nMAssay Description:Inhibition of human recombinant MAO-B after 15 minsMore data for this Ligand-Target Pair