BDBM50114608 (1E)-1-(3,4-dichlorophenyl)propan-1-one thiosemicarbazone::CHEMBL92099
SMILES CCC(=NNC(N)=S)c1ccc(Cl)c(Cl)c1
InChI Key InChIKey=RVTBBZNNLYWUCX-UHFFFAOYSA-N
Data 7 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50114608
Affinity DataIC50: 20nMAssay Description:Inhibitory activity against Trypanosoma cruzi cathepsin L-like protease (cruzain) was determined using purified recombinant proteinMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibitory concentration against cruzain of Trypanosoma cruziMore data for this Ligand-Target Pair
TargetCysteine protease(Trypanosoma brucei rhodesiense)
University Of California San Francisco
Curated by ChEMBL
University Of California San Francisco
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibitory concentration against rhodesain of Trypanosoma brucei rhodesienceMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant Trypanosoma cruzi Tulahuen 2 cruzain incubated for 5 mins folllowed by Z-Phe-Arg-AMC substrate by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibition of epimastigote form of Trypanosoma cruzi Tulahuen 2 cruzain assessed as reduction in 7-amino-4-methylcoumarin release incubated for 20 mi...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant Trypanosoma cruzi Tulahuen 2 cruzain incubated for 5 mins folllowed by Z-Phe-Arg-AMC substrate by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 69nMAssay Description:Inhibition of epimastigote form of Trypanosoma cruzi Tulahuen 2 cruzain assessed as reduction in 7-amino-4-methylcoumarin release incubated for 20 mi...More data for this Ligand-Target Pair