BDBM50135527 (-)-cis-rotenone::(-)-rotenone::(2R,6aS,12aS)-8,9-dimethoxy-2-(prop-1-en-2-yl)-1,2,12,12a-tetrahydrochromeno[3,4-b]furo[2,3-h]chromen-6(6aH)-one::5'beta-rotenone::Barbasco::CHEMBL429023::Canex::Noxfire::[2R-(2alpha,6aalpha,12aalpha)]-1,2,12,12a-tetrahydro-8,9-dimethoxy-2-(1-methylethenyl)[1]benzopyrano[3,4-b]furo[2,3-H][1]benzopyran-6(6aH)-one::rotenone
SMILES COc1cc2OC[C@H]3Oc4c5C[C@@H](Oc5ccc4C(=O)[C@H]3c2cc1OC)C(C)=C
InChI Key InChIKey=JUVIOZPCNVVQFO-HBGVWJBISA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 11 hits for monomerid = 50135527
TargetAcyl carrier protein,/NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial(Bovine)
Universidad De Valencia
Curated by ChEMBL
Universidad De Valencia
Curated by ChEMBL
Affinity DataIC50: 5.10nMAssay Description:Inhibitory activity against NADH oxidase in beef heart mitochondrial complex I.More data for this Ligand-Target Pair
Affinity DataIC50: 3.5nMAssay Description:The compound was evaluated for the inhibition of NADH dehydrogenaseMore data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of pig pancreatic lipase assessed as hydrolysis of p-nitrophenylbutyrate to p-nitrophenolMore data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(malaria parasite P. falciparum)
Harvard School of Public Health
Curated by ChEMBL
Harvard School of Public Health
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Plasmodium falciparum DHODMore data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (fumarate)(Baker's yeast)
Harvard School of Public Health
Curated by ChEMBL
Harvard School of Public Health
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Saccharomyces cerevisiae DHODMore data for this Ligand-Target Pair
TargetNADH-ubiquinone oxidoreductase chain 1(Bovine)
Universidad Polit£Cnica De Valencia
Curated by ChEMBL
Universidad Polit£Cnica De Valencia
Curated by ChEMBL
Affinity DataIC50: 4.40nMAssay Description:Inhibition of Bos taurus (beef) heart NAD1More data for this Ligand-Target Pair
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human MRP3 overexpressed in Sf9 insect cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ...More data for this Ligand-Target Pair
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of human BSEP overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-taurocholate in presence of ATP measured after 15 to ...More data for this Ligand-Target Pair
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Illinois
Curated by ChEMBL
University of Illinois
Curated by ChEMBL
Affinity DataIC50: >5.07E+5nMAssay Description:Inhibition of HIV1 RTMore data for this Ligand-Target Pair
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human MRP2 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair