BDBM50152917 CHEMBL361376::N-Hydroxy-2-{3-[4-(2-methyl-quinolin-4-ylmethoxy)-benzenesulfonylmethyl]-oxetan-3-yl}-acetamide
SMILES Cc1cc(COc2ccc(cc2)S(=O)(=O)CC2(CC(=O)NO)COC2)c2ccccc2n1
InChI Key InChIKey=JTEXDSSTTHRJGK-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50152917
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 595nMAssay Description:Effect on TNF-Alpha release in LPS-stimulated human whole blood assayMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Sus scrofa (pig))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of porcine Tumor necrosis factor- alpha converting enzyme (TACE, ADAM17)More data for this Ligand-Target Pair