BDBM50232166 CHEMBL4071588
SMILES Oc1ccc(cc1)-c1ccc(s1)C(=O)c1c(F)ccc(O)c1F
InChI Key InChIKey=HDNHNXBACWULOX-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50232166
Affinity DataIC50: 3nMAssay Description:Inhibition of human placental cytosolic 17beta-HSD1 assessed as reduction in activation of [2,4,6,7-3H]-E1 substrate to E2 after 10 mins in presence ...More data for this Ligand-Target Pair
Affinity DataIC50: 71nMAssay Description:Inhibition of human placental microsomal 17beta-HSD2 using [2,4,6,7-3H]-E2 as substrate after 20 mins in presence of NAD+ by RP-HPLC methodMore data for this Ligand-Target Pair
Affinity DataIC50: 3.10nMAssay Description:Inhibition of human placental cytosolic 17beta-HSD1 using [3H]-E1/E1 substrate and NADH after 10 mins by HPLC based radio-detection methodMore data for this Ligand-Target Pair
Affinity DataIC50: 7.90nMAssay Description:Inhibition of 17beta-HSD1 in human T47D cells preincubated for 1 hr followed by addition of [3H]-E1/E1 as substrate measured after 30 mins by HPLC ba...More data for this Ligand-Target Pair
Affinity DataIC50: 71nMAssay Description:Inhibition of human placental cytosolic 17beta-HSD2 using [3H]-E2/E2 substrate and NAD+ after 20 mins by HPLC based radio-detection methodMore data for this Ligand-Target Pair