BDBM50244718 CHEMBL460273::JNJ-1661010::N-phenyl-4-(3-phenyl-1,2,4-thiadiazol-5-yl)piperazine-1-carboxamide::cid_2809273
SMILES O=C(Nc1ccccc1)N1CCN(CC1)c1nc(ns1)-c1ccccc1
InChI Key InChIKey=BHBOSTKQCZEAJM-UHFFFAOYSA-N
Data 11 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 11 hits for monomerid = 50244718
TargetUbiquitin-conjugating enzyme E2 N(Human)
Burnham Center For Chemical Genomics
Curated by PubChem BioAssay
Burnham Center For Chemical Genomics
Curated by PubChem BioAssay
Affinity DataIC50: >2.00E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego CA...More data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Human)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of human FAAH preincubated for 40 minsMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Human)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 70nMAssay Description:Inhibition of human FAAH preincubated for 10 minsMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 34nMAssay Description:Inhibition of rat FAAH preincubated for 20 minsMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Human)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 33nMAssay Description:Inhibition of human FAAH preincubated for 20 minsMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Human)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Apparent inhibition of human FAAH expressed in CHO-K1 cells using ethanolamine 1-3[H] as substrate after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Human)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of rat FAAH assessed as hydrolysis of anandamidoaminomethylcumarinMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Human)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 34nMAssay Description:Inhibition of rat FAAHMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Human)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of human FAAH after 60 minsMore data for this Ligand-Target Pair