BDBM50322941 2-(3-chlorophenyl)-N-(3,4-difluorophenyl)-1-oxo-3-(pyridin-2-yl)-2,7-diazaspiro[3.5]nonane-7-carboxamide::CHEMBL1210692
SMILES Fc1ccc(NC(=O)N2CCC3(CC2)C(N(C3=O)c2cccc(Cl)c2)c2ccccn2)cc1F
InChI Key InChIKey=GJRHWNWQCQVPBA-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50322941
TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Homo sapiens (Human))
Merck Research Laboratory
Curated by ChEMBL
Merck Research Laboratory
Curated by ChEMBL
Affinity DataIC50: 116nMAssay Description:Inhibition of human CaV3.2 expressed in HEK293 cells at -100 mV membrane potential by Ionworks HT assayMore data for this Ligand-Target Pair
TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Homo sapiens (Human))
Merck Research Laboratory
Curated by ChEMBL
Merck Research Laboratory
Curated by ChEMBL
Affinity DataIC50: 118nMAssay Description:Inhibition of human CaV3.2 expressed in HEK293 cells at -100 mV membrane potential by whole cell path clamp methodMore data for this Ligand-Target Pair
TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Homo sapiens (Human))
Merck Research Laboratory
Curated by ChEMBL
Merck Research Laboratory
Curated by ChEMBL
Affinity DataIC50: 116nMAssay Description:Inhibition of human CaV3.2 expressed in HEK293 cells at -100 mV membrane potential by Ionworks HT assayMore data for this Ligand-Target Pair