BDBM50379209 CHEMBL2011282
SMILES COc1ccc(CCNC(=O)c2cc(=O)c3c(OCc4ccccc4)cccc3o2)cc1OC
InChI Key InChIKey=NRWKOPKPCJMFGI-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50379209
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
University of Regensburg
Curated by ChEMBL
University of Regensburg
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Inhibition of human ABCG2 expressed in HEK293 cells by mitoxantrone flow cytometric analysisMore data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
University of Regensburg
Curated by ChEMBL
University of Regensburg
Curated by ChEMBL
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of ABCG2 in human MCF7/Topo cells by Hoechst 33342 assayMore data for this Ligand-Target Pair
Affinity DataIC50: 194nMAssay Description:Inhibition of sulfasalazine-stimulated ABCB1 ATPase activity (unknown origin) expressed in baculovirus infected Sf9 insect cells using ATP as substra...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
University of Regensburg
Curated by ChEMBL
University of Regensburg
Curated by ChEMBL
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of ABCG2 in topotecan-cultured human MCF7 cells using Hoechst 33342 as substrate measured after 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
University of Regensburg
Curated by ChEMBL
University of Regensburg
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Inhibition of ABCG2-mediated mitoxantrone efflux in HEK293 cells by flow cytometryMore data for this Ligand-Target Pair