BDBM50433629 CHEMBL2380845
SMILES O=C(Nc1ccc(Nc2ccnc3[nH]c(=O)c4ccccc4c23)cc1)c1ccccc1
InChI Key InChIKey=XLSPYLMTRXPYKY-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 50433629
TargetHigh affinity nerve growth factor receptor(Human)
Emd-Serono Research Institute
Curated by ChEMBL
Emd-Serono Research Institute
Curated by ChEMBL
Affinity DataIC50: 819nMAssay Description:Inhibition of TrkA (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 401nMAssay Description:Inhibition of WNK3 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 211nMAssay Description:Inhibition of SIK (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 149nMAssay Description:Inhibition of ACK1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of aurora-B (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 36nMAssay Description:Inhibition of LIMK1 (unknown origin)More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Emd-Serono Research Institute
Curated by ChEMBL
Emd-Serono Research Institute
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of Ret (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 208nMAssay Description:Inhibition of aurora-B in human MIAPaCa2 cells assessed as reduction of phosphorylation of histone H3More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of aurora-A (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 41nMAssay Description:Inhibition of CHK2 (unknown origin)More data for this Ligand-Target Pair