BDBM50464867 CHEMBL4289783
SMILES Fc1ccc(N2CCN(CCCc3c[nH]c4ccc(F)cc34)CC2)c(c1)-c1ccccc1
InChI Key InChIKey=GPVZPQVIHIFYGO-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50464867
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Shanghai Institute of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 1.67E+4nMAssay Description:Inhibition of human ERG expressed in CHO-K1 cells assessed as reduction in tail current amplitude at -80 mV holding potential after 2 mins by path cl...More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Shanghai Institute of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of [3H]serotonin reuptake in rat brain synaptosomes SERT after 15 mins by TopCount scintillation counting methodMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Shanghai Institute of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 177nMAssay Description:Inhibition of serotonin transporter in rat brain tissue assessed as inhibition of [3H]-5-hydroxytryptamine reuptakeMore data for this Ligand-Target Pair