BDBM192755 TG101209::US11279703, TABLE 6.171::US11643396, Example TG101209

SMILES CN1CCN(CC1)c1ccc(Nc2ncc(C)c(Nc3cccc(c3)S(=O)(=O)NC(C)(C)C)n2)cc1

InChI Key InChIKey=JVDOKQYTTYUYDV-UHFFFAOYSA-N

Data  40 IC50  2 Kd

PDB links: 3 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 192755   

TargetBromodomain-containing protein 4(Homo sapiens (Human))TBA
LigandPNGBDBM192755(TG101209 | US11279703, TABLE 6.171 | US11643396, E...)
Affinity DataKd:  123nMAssay Description:Binding affinity to recombinant human His6-TEV protease-tagged BRD4 bromodomain 1 expressed in bacteria by isothermal titration calorimetric methodMore data for this Ligand-Target Pair
TargetBromodomain testis-specific protein(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM192755(TG101209 | US11279703, TABLE 6.171 | US11643396, E...)
Affinity DataKd:  123nMAssay Description:Binding affinity to human N-terminal His6-tagged BRDTexpressed in Escherichia coli BL21 (DE3) cells (21 to 137 residues) incubated for 1 hrMore data for this Ligand-Target Pair
In DepthDetails PubMed