BDBM50163867 CHEMBL2443189::carbonic anhydrase (CA) inhibitors, benzenesulphonamide ligand, 9
SMILES NS(=O)(=O)c1cccc(c1)C(=O)CSc1ncccn1
InChI Key InChIKey=BWAZRCOFUQSGBG-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 22 hits for monomerid = 50163867
Affinity DataKd: 3.33E+3nMAssay Description:Binding affinity to human recombinant carbonic anhydrase 12 by thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 2.20E+3nMAssay Description:Binding affinity to human recombinant CA7 after 30 secs by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKd: 710nMAssay Description:Binding affinity to human recombinant CA13 after 30 secs by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKd: 500nMAssay Description:Binding affinity to human recombinant CA13 by fluorescence-based thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 1.30E+3nMAssay Description:Binding affinity to human recombinant CA12 catalytic domain by fluorescence-based thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 1.20E+3nMAssay Description:Binding affinity to human recombinant CA1 expressed in Escherichia coli after 30 secs by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKd: 330nMAssay Description:Binding affinity to human recombinant CA1 expressed in Escherichia coli by fluorescence-based thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 2.00E+3nMAssay Description:Binding affinity to human recombinant CA7 by fluorescence-based thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 520nMAssay Description:Binding affinity to human recombinant CA2 expressed in Escherichia coli after 30 secs by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKd: 430nMAssay Description:Binding affinity to human recombinant CA2 expressed in Escherichia coli by fluorescence-based thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 260nMAssay Description:Binding affinity to human recombinant CA9 catalytic domain after 30 secs by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKd: 330nMAssay Description:Binding affinity to human recombinant CA9 catalytic domain by fluorescence-based thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 1.10nMAssay Description:Binding affinity to human full length His-tagged CA2 (1 to 260 residues) expressed in Escherichia coli BL21(DE3) assessed as intrinsic thermodynamic ...More data for this Ligand-Target Pair
Affinity DataKd: 3.90nMAssay Description:Binding affinity to CA7 (unknown origin) assessed as intrinsic thermodynamic equilibrium constant at pH 7 by SPR assayMore data for this Ligand-Target Pair
Affinity DataKd: 0.330nMAssay Description:Binding affinity to human CA9 catalytic domain expressed in mammalian expression system assessed as intrinsic thermodynamic equilibrium constant at p...More data for this Ligand-Target Pair
Affinity DataKd: 6.80nMAssay Description:Inhibition of Topoisomerase I by cleavage complex formation in intact human HL-60 cellsMore data for this Ligand-Target Pair
Affinity DataKd: 4nMAssay Description:Binding affinity to human N-terminal full length His-tagged CA13 (1 to 262 residues) expressed in Escherichia coli BL21(DE3) assessed as intrinsic th...More data for this Ligand-Target Pair
Affinity DataKd: 1.11E+3nMAssay Description:Binding affinity to human recombinant carbonic anhydrase 2 by thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 1.33E+3nMAssay Description:Binding affinity to human recombinant carbonic anhydrase 13 by thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 769nMAssay Description:Binding affinity to human recombinant carbonic anhydrase 1 expressed in Escherichia coli BL21 (DE3) by thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 1.90E+3nMAssay Description:Binding affinity to human recombinant carbonic anhydrase 6 expressed in Escherichia coli Rosetta2 (DE3) by thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 4.00E+3nMAssay Description:Binding affinity to human recombinant carbonic anhydrase 7 by thermal shift assayMore data for this Ligand-Target Pair