BDBM50355496 CHEMBL1908397
SMILES O=C(N1CCNCC1)c1ccc(\C=C\c2n[nH]c3ccccc23)cc1
InChI Key InChIKey=YYLKKYCXAOBSRM-JXMROGBWSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 454 hits for monomerid = 50355496
Affinity DataKd: 360nMAssay Description:Binding constant for ABL1(F317L)-nonphosphorylated kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 1.30E+3nMAssay Description:Binding constant for FLT4 kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 570nMAssay Description:Binding constant for MET(Y1235D) kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 2.10E+3nMAssay Description:Binding constant for DMPK2 kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 17nMAssay Description:Binding constant for ABL1(H396P)-nonphosphorylated kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for TNNI3K kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 240nMAssay Description:Binding constant for KIT(D816H) kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for EGFR(L747-S752del, P753S) kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for RSK4(Kin.Dom.2-C-terminal) kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for EGFR kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 1.90E+3nMAssay Description:Binding constant for BRSK1 kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 12nMAssay Description:Binding constant for ABL1(T315I)-nonphosphorylated kinase domainMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Ambit Biosciences
Curated by ChEMBL
Ambit Biosciences
Curated by ChEMBL
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for PIK3CA(E545A) kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 13nMAssay Description:Binding constant for FLT3(D835H) kinase domainMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha(Human)
Ambit Biosciences
Curated by ChEMBL
Ambit Biosciences
Curated by ChEMBL
Affinity DataKd: 4.00E+3nMAssay Description:Binding constant for CAMK2A kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 35nMAssay Description:Binding constant for RET(V804L) kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 63nMAssay Description:Binding constant for ABL1-nonphosphorylated kinase domainMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Ambit Biosciences
Curated by ChEMBL
Ambit Biosciences
Curated by ChEMBL
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for PIK3CA(H1047Y) kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 740nMAssay Description:Binding constant for MYLK kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 36nMAssay Description:Binding constant for ABL1(E255K)-phosphorylated kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 1.50E+3nMAssay Description:Binding constant for EPHA6 kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 400nMAssay Description:Binding constant for INSR kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 12nMAssay Description:Binding constant for KIT(V559D,T670I) kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 7.10E+3nMAssay Description:Binding constant for EGFR(E746-A750del) kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 35nMAssay Description:Binding constant for RET(V804M) kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 75nMAssay Description:Binding constant for ABL1-phosphorylated kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 88nMAssay Description:Binding constant for AURKB kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 160nMAssay Description:Binding constant for KIT(D816V) kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 19nMAssay Description:Binding constant for ABL1(M351T)-phosphorylated kinase domainMore data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Human)
Ambit Biosciences
Curated by ChEMBL
Ambit Biosciences
Curated by ChEMBL
Affinity DataKd: 180nMAssay Description:Binding constant for IKK-alpha kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 53nMAssay Description:Binding constant for KIT kinase domainMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Ambit Biosciences
Curated by ChEMBL
Ambit Biosciences
Curated by ChEMBL
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for PIK3CA(H1047L) kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 820nMAssay Description:Binding constant for CDK4-cyclinD1 kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 240nMAssay Description:Binding constant for IRAK3 kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 36nMAssay Description:Binding constant for ABL1(Y253F)-phosphorylated kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for BRAF kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 94nMAssay Description:Binding constant for ABL1(F317L)-phosphorylated kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for EGFR(L747-T751del,Sins) kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 47nMAssay Description:Binding constant for RET(M918T) kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 4.60E+3nMAssay Description:Binding constant for EGFR(G719S) kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 710nMAssay Description:Binding constant for CHEK1 kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 470nMAssay Description:Binding constant for CAMKK2 kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 1.60E+3nMAssay Description:Binding constant for MAP3K4 kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for RPS6KA5(Kin.Dom.1-N-terminal) kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 22nMAssay Description:Binding constant for ABL1(Q252H)-phosphorylated kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for RSK1(Kin.Dom.2-C-terminal) kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 6.00E+3nMAssay Description:Binding constant for MYO3B kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 1.20E+3nMAssay Description:Binding constant for FGFR3 kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 1.60E+3nMAssay Description:Binding constant for ABL1(F317I)-nonphosphorylated kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 810nMAssay Description:Binding constant for MST1R kinase domainMore data for this Ligand-Target Pair