BDBM50466038 CHEMBL4281823
SMILES CCn1cc(-c2ccc3N(CCc3c2)C(=O)Cc2cccc(OC(F)(F)F)c2)c2c(N)ncnc12
InChI Key InChIKey=APPXQUDJLJXULP-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50466038
TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Sichuan University/Collaborative Innovation Center of Biotherapy
Curated by ChEMBL
Sichuan University/Collaborative Innovation Center of Biotherapy
Curated by ChEMBL
Affinity DataKd: 4.40nMAssay Description:Binding affinity to wild-type human partial length RIPK1 (M1 to K305 residues) expressed in bacterial expression system by Kinomescan methodMore data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 4(Homo sapiens (Human))
Sichuan University/Collaborative Innovation Center of Biotherapy
Curated by ChEMBL
Sichuan University/Collaborative Innovation Center of Biotherapy
Curated by ChEMBL
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to wild-type human partial length RIPK4 (M1 to V303 residues) expressed in mammalian expression system by Kinomescan methodMore data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 3(Homo sapiens (Human))
Sichuan University/Collaborative Innovation Center of Biotherapy
Curated by ChEMBL
Sichuan University/Collaborative Innovation Center of Biotherapy
Curated by ChEMBL
Affinity DataKd: 7.20E+3nMAssay Description:Binding affinity to wild-type human partial length RIPK3 (M1 to Q307 residues) expressed in bacterial expression system by Kinomescan methodMore data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Sichuan University/Collaborative Innovation Center of Biotherapy
Curated by ChEMBL
Sichuan University/Collaborative Innovation Center of Biotherapy
Curated by ChEMBL
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to wild-type human partial length RIPK2 (M1 to K310 residues) expressed in bacterial expression system by Kinomescan methodMore data for this Ligand-Target Pair