BDBM181119 US9138393, Cimetidine::US9144538, Cimetidine
SMILES CN\C(NC#N)=N\CCSCc1nc[nH]c1C
InChI Key InChIKey=AQIXAKUUQRKLND-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 181119
Affinity DataKi: 490nMAssay Description:Displacement of [125I]APT from human recombinant histamine H2 receptor expressed in CHO cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Cytochrome P450 is a large and diverse group of enzymes that catalyze the oxidation of organic substances. Some members of the CYP family contribute ...More data for this Ligand-Target Pair
Affinity DataIC50: >1.35E+5nMAssay Description:Inhibition of human BSEP expressed in fall armyworm sf9 cell plasma membrane vesicles assessed as reduction in vesicle-associated [3H]-taurocholate t...More data for this Ligand-Target Pair
Affinity DataIC50: 1.49E+5nMAssay Description:Inhibition of human OCT1 expressed in HEK293 cells assessed as decrease in uptake of YM155 after 1 minMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:A commercially available P450-GLO Assay kit (Promega Corporation, Madison Wis.) is used to screen various compounds for CYP3A4A inhibition activity. ...More data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Displacement of [125I]APT from human recombinant histamine H2 receptor expressed in CHO cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair