BDBM183990 US9150566, 27
SMILES Cc1ccc(C(=O)N2CCOC[C@H]2Cc2cccc(c2)-n2nccn2)c(c1)-n1nccn1
InChI Key InChIKey=GKPHAIOJCHBZCT-HXUWFJFHSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 183990
Affinity DataIC50: 2nMT: 37°CAssay Description:Chinese hamster ovary (CHO) cells expressing the human orexin-1 receptor and the human orexin-2 receptor, respectively, are grown in culture medium (...More data for this Ligand-Target Pair
Affinity DataIC50: 3.10E+4nMpH: 7.4 T: 37°CAssay Description:The CYP3A4 inhibition assay was performed using human liver microsomes and testosterone 6'-hydroxylation as a P450 isoform-specific marker. In a tota...More data for this Ligand-Target Pair
Affinity DataIC50: 274nMT: 37°CAssay Description:Chinese hamster ovary (CHO) cells expressing the human orexin-1 receptor and the human orexin-2 receptor, respectively, are grown in culture medium (...More data for this Ligand-Target Pair