BDBM50001728 8-Chloro-1-methyl-6-phenyl-4H-s-triazolo(4,3-a)(1,4)benzodiazepine::8-chloro-1-methyl-6-phenyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine::ALPRAZOLAM::CHEMBL661::Xanax
SMILES Cc1nnc2CN=C(c3ccccc3)c3cc(Cl)ccc3-n12
InChI Key InChIKey=VREFGVBLTWBCJP-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 20 hits for monomerid = 50001728
TargetGamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2(Human)
University of Wisconsin-Milwaukee
Curated by ChEMBL
University of Wisconsin-Milwaukee
Curated by ChEMBL
Affinity DataKi: 0.600nMAssay Description:Displacement of [3H]flunitrazepam from human recombinant alpha2beta2gamma2 GABAA receptor expressed in HEK cell membrane by competitive radioligand b...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Human)
University of Wisconsin-Milwaukee
Curated by ChEMBL
University of Wisconsin-Milwaukee
Curated by ChEMBL
Affinity DataKi: 0.800nMAssay Description:Displacement of [3H]flunitrazepam from human recombinant alpha1beta2gamma2 GABAA receptor expressed in HEK cell membrane by competitive radioligand b...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-2/gamma-2(Human)
University of Wisconsin-Milwaukee
Curated by ChEMBL
University of Wisconsin-Milwaukee
Curated by ChEMBL
Affinity DataKi: 1.40nMAssay Description:Displacement of [3H]flunitrazepam from human recombinant alpha3beta2gamma2 GABAA receptor expressed in HEK cell membrane by competitive radioligand b...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-5/beta-2/gamma-2(Human)
University of Wisconsin-Milwaukee
Curated by ChEMBL
University of Wisconsin-Milwaukee
Curated by ChEMBL
Affinity DataKi: 1.5nMAssay Description:Displacement of [3H]flunitrazepam from human recombinant alpha5beta2gamma2 GABAA receptor expressed in HEK cell membrane by competitive radioligand b...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid (GABA) B receptor 1(Rat)
Georgetown University
Curated by PDSP Ki Database
Georgetown University
Curated by PDSP Ki Database
TargetGamma-aminobutyric acid (GABA) B receptor 1(Rat)
Georgetown University
Curated by PDSP Ki Database
Georgetown University
Curated by PDSP Ki Database
TargetGamma-aminobutyric acid (GABA) B receptor 1(Rat)
Georgetown University
Curated by PDSP Ki Database
Georgetown University
Curated by PDSP Ki Database
TargetGamma-aminobutyric acid (GABA) B receptor 1(Rat)
Georgetown University
Curated by PDSP Ki Database
Georgetown University
Curated by PDSP Ki Database
TargetGamma-aminobutyric acid (GABA) B receptor 1(Rat)
Georgetown University
Curated by PDSP Ki Database
Georgetown University
Curated by PDSP Ki Database
TargetGamma-aminobutyric acid receptor subunit alpha-1(Rat)
Georgetown University
Curated by PDSP Ki Database
Georgetown University
Curated by PDSP Ki Database
TargetGamma-aminobutyric acid receptor subunit alpha-1(Rat)
Georgetown University
Curated by PDSP Ki Database
Georgetown University
Curated by PDSP Ki Database
Affinity DataEC50: 37nMAssay Description:Effective concentration against gamma-aminobutyric acid (GABA) A receptor, alpha 1More data for this Ligand-Target Pair
Affinity DataEC50: 69nMAssay Description:Effective concentration against gamma-aminobutyric acid (GABA) A receptor, alpha 3More data for this Ligand-Target Pair
Affinity DataEC50: 10nMAssay Description:Effective concentration against Gamma-aminobutyric acid A receptor, alpha 5More data for this Ligand-Target Pair
Affinity DataKd: 2.46E+3nMAssay Description:Binding affinity to BRD4-BD1 by isothermal titration calorimetryMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Human)
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Displacement of [125I]-gastrin from guinea pig gastric glandsMore data for this Ligand-Target Pair
TargetCholecystokinin receptor type A(Rat)
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 6.40E+4nMAssay Description:Displacement of [125I]-CCK from Cholecystokinin receptor of rat pancreasMore data for this Ligand-Target Pair
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of PAF-induced platelet aggregation in rabbit platelet rich plasmaMore data for this Ligand-Target Pair
Affinity DataEC50: 12nMAssay Description:Effective concentration against gamma-aminobutyric acid (GABA) A receptor, alpha 2More data for this Ligand-Target Pair