BDBM50029689 CHEMBL3353411
SMILES COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1nccc(n1)-c1c[nH]c2ccccc12
InChI Key InChIKey=IQNVEOMHJHBNHC-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50029689
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of EGFR L858R/T970M double mutant phosphorylation in human NCI-H1975 cells after 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of EGFR exon 19 deletion activating mutant phosphorylation in human PC9 cells after 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of wild type EGFR phosphorylation in human LoVo cells after 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:Inhibition of wild type EGFR phosphorylation in human LoVo cells preincubated for 2 hrs followed by EGF stimulation measured after 30 mins by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 2.63E+5nMAssay Description:Inhibition of IGF1R (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of EGFR Del ex19 mutant phosphorylation in human PC9 cells preincubated for 2 hrs by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of EGFR T790M/L858R double mutant phosphorylation in human H1975 cells preincubated for 2 hrs by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 1.75E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair