BDBM50131432 CHEMBL533::Corvert::IBUTILIDE::N-(4-(4-(ethyl(heptyl)amino)-1-hydroxybutyl)phenyl)methanesulfonamide::N-{4-[4-(Ethyl-heptyl-amino)-1-hydroxy-butyl]-phenyl}-methanesulfonamide

SMILES CCCCCCCN(CC)CCCC(O)c1ccc(NS(C)(=O)=O)cc1

InChI Key InChIKey=ALOBUEHUHMBRLE-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50131432   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Tcg Lifesciences

Curated by ChEMBL
LigandPNGBDBM50131432(CHEMBL533 | Corvert | IBUTILIDE | N-(4-(4-(ethyl(h...)
Affinity DataIC50:  15.1nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Tcg Lifesciences

Curated by ChEMBL
LigandPNGBDBM50131432(CHEMBL533 | Corvert | IBUTILIDE | N-(4-(4-(ethyl(h...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human Potassium channel HERG expressed in mammalian cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

LigandPNGBDBM50131432(CHEMBL533 | Corvert | IBUTILIDE | N-(4-(4-(ethyl(h...)
Affinity DataIC50:  6.25E+4nMAssay Description:Inhibition of Cav1.2 current measured using QPatch automatic path clamp system in CHO cells expressing Cav1.2, beta-2 and alpha-2/delta-1 subunitsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Tcg Lifesciences

Curated by ChEMBL
LigandPNGBDBM50131432(CHEMBL533 | Corvert | IBUTILIDE | N-(4-(4-(ethyl(h...)
Affinity DataIC50:  10nMAssay Description:Inhibitory concentration against potassium channel HERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Tcg Lifesciences

Curated by ChEMBL
LigandPNGBDBM50131432(CHEMBL533 | Corvert | IBUTILIDE | N-(4-(4-(ethyl(h...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human ERG expressed in CHO cells by whole cell patch clamp techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Tcg Lifesciences

Curated by ChEMBL
LigandPNGBDBM50131432(CHEMBL533 | Corvert | IBUTILIDE | N-(4-(4-(ethyl(h...)
Affinity DataIC50:  20nMAssay Description:Inhibitory concentration against IKr potassium channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank