BDBM50291090 (6,7-Dimethoxy-quinazolin-4-yl)-p-tolyl-amine; hydrochloride::CHEMBL1191611::CHEMBL542733::US10548897, Compound 3
SMILES COc1ccc(Nc2ncnc3cc(OC)c(OC)cc23)cc1
InChI Key InChIKey=AHZHKZBDSLBFFP-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50291090
Affinity DataIC50: 250nMAssay Description:Inhibition of Epidermal growth factor receptor autophosphorylation.More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of p56 Lck tyrosine kinase in Jurkat cells where p56lck autophosphorylation is inhibited.More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:The ATP-biotin assay was performed in buffer containing 25 mM Tris pH 7.5, 150 mM NaCl, 10 mM MgCl2, and 2% DMSO. Purified hKSR2-rMEK1 was assayed at...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Rat)
Rajiv Gandhi Proudyogiki Vishwavidyalaya
Curated by ChEMBL
Rajiv Gandhi Proudyogiki Vishwavidyalaya
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of rat recombinant GST-fused DYRK1A expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate by scintillation counting in presence ...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 5 activator 1(Human)
Rajiv Gandhi Proudyogiki Vishwavidyalaya
Curated by ChEMBL
Rajiv Gandhi Proudyogiki Vishwavidyalaya
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:inhibition of human recombinant CDK5/p25 using histone H1 as substrate by scintillation counting in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK1(Human)
Rajiv Gandhi Proudyogiki Vishwavidyalaya
Curated by ChEMBL
Rajiv Gandhi Proudyogiki Vishwavidyalaya
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant GST-fused CLK1 expressed in Escherichia coli using GRSRSRSRSRSR as substrateMore data for this Ligand-Target Pair