BDBM12779 (2S)-N-[4-(1H-1,3-benzodiazol-1-yl)-2-fluorophenyl]-2-(5-carbamimidoyl-1H-indol-3-yl)-3-phenylpropanamide::(S)-(+)::5-amidinoindole 13c

SMILES NC(=N)c1ccc2[nH]cc([C@H](Cc3ccccc3)C(=O)Nc3ccc(cc3F)-n3cnc4ccccc34)c2c1

InChI Key InChIKey=OREKERSNHHDONJ-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 12779   

TargetCoagulation factor X(Human)
Bristol-Myers Squibb

LigandPNGBDBM12779((2S)-N-[4-(1H-1,3-benzodiazol-1-yl)-2-fluorophenyl...)
Affinity DataKi:  26nM ΔG°:  -10.2kcal/molepH: 7.0 T: 2°CAssay Description:Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2007
Entry Details Article
PubMed
TargetCoagulation factor IX(Human)
Bristol-Myers Squibb

LigandPNGBDBM12779((2S)-N-[4-(1H-1,3-benzodiazol-1-yl)-2-fluorophenyl...)
Affinity DataKi:  820nMAssay Description:Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2007
Entry Details Article
PubMed