BDBM666969 1004::US20240116946, Example 1003::US20240116946, Example 1004

SMILES COc1cc(-c2cc3n(CCC#N)c(=O)n(-c4cncc5cnn(C)c45)c(=O)c3s2)c(cc1F)C#N

InChI Key InChIKey=FULGGBIXAOBEQT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 666969   

TargetReplicase polyprotein 1a(2019-nCoV)
Gilead Sciences

US Patent
LigandPNGBDBM666969(US20240116946, Example 1003 | 1004 | US20240116946...)
Affinity DataIC50: 2.83nMAssay Description:This biochemical assay measured small molecule inhibitor IC50 values against recombinant SARS-CoV-2 Main protease (Mpro). Compounds from 100 μM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Gilead Sciences

US Patent
LigandPNGBDBM666969(US20240116946, Example 1003 | 1004 | US20240116946...)
Affinity DataIC50: 71.5nMAssay Description:This biochemical assay measured small molecule inhibitor IC50 values against recombinant SARS-CoV-2 Main protease (Mpro). Compounds from 100 μM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
US Patent