BDBM666978 1013::US20240116946, Example 1012::US20240116946, Example 1013

SMILES COc1cc(-c2cc3n(CC#N)c(=O)n(-c4cncc5cnn(C)c45)c(=O)c3s2)c(Cl)cc1F

InChI Key InChIKey=UXOXMUWZAXIDDJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 666978   

TargetReplicase polyprotein 1a(2019-nCoV)
Gilead Sciences

US Patent
LigandPNGBDBM666978(US20240116946, Example 1012 | 1013 | US20240116946...)
Affinity DataIC50: 1.42nMAssay Description:This biochemical assay measured small molecule inhibitor IC50 values against recombinant SARS-CoV-2 Main protease (Mpro). Compounds from 100 μM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Gilead Sciences

US Patent
LigandPNGBDBM666978(US20240116946, Example 1012 | 1013 | US20240116946...)
Affinity DataIC50: 1.99nMAssay Description:This biochemical assay measured small molecule inhibitor IC50 values against recombinant SARS-CoV-2 Main protease (Mpro). Compounds from 100 μM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
US Patent