BDBM50047019 11h::7-Methoxy-1-methyl-9H-beta-carboline::7-Methoxy-1-methyl-9H-beta-carboline (harmine)::7-methoxy-1-methyl-9H-pyrido[3,4-b]indole::CHEMBL269538::HARMINE

SMILES COc1ccc2c(c1)[nH]c3c(C)nccc23

InChI Key InChIKey=BXNJHAXVSOCGBA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50047019   

TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50047019BDBM50047019(CHEMBL269538 | 7-methoxy-1-methyl-9H-pyrido[3,4-b]...)
Affinity DataIC50: 21nMAssay Description:Inhibition of DYRK1A (unknown origin) using DYRKtide as substrate incubated for 60 mins in presence of ATP by ADP-glo reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase haspin(Human)
University of Salerno

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50047019BDBM50047019(CHEMBL269538 | 7-methoxy-1-methyl-9H-pyrido[3,4-b]...)
Affinity DataIC50: 590nMAssay Description:Inhibition of haspin (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed