BDBM544452 24::US11285226, Compound 18e

SMILES CN1CCN(CC1)c1ccc(cc1)C(=C(\CCCO)c1ccccc1)\c1ccc(Br)cc1

InChI Key InChIKey=RVPDDVIQFCWUAC-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 544452   

TargetEstrogen-related receptor gamma(Human)
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM544452(24 | US11285226, Compound 18e)
Affinity DataIC50: 60nMAssay Description:In an ERR alpha binding assay, GST-bound ERR alpha LBD was used, and all experiments other than that was the same as the ERR gamma binding assay.In a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2022
Entry Details
US Patent

TargetSteroid hormone receptor ERR2(Human)
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM544452(24 | US11285226, Compound 18e)
Affinity DataIC50: 2.80E+3nMAssay Description:In an ERR alpha binding assay, GST-bound ERR alpha LBD was used, and all experiments other than that was the same as the ERR gamma binding assay.In a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2022
Entry Details
US Patent

TargetSteroid hormone receptor ERR1(Human)
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM544452(24 | US11285226, Compound 18e)
Affinity DataIC50: 1.00E+4nMAssay Description:In an ERR alpha binding assay, GST-bound ERR alpha LBD was used, and all experiments other than that was the same as the ERR gamma binding assay.In a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2022
Entry Details
US Patent

TargetEstrogen receptor(Human)
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM544452(24 | US11285226, Compound 18e)
Affinity DataIC50: 1.00E+4nMAssay Description:In an ERR alpha binding assay, GST-bound ERR alpha LBD was used, and all experiments other than that was the same as the ERR gamma binding assay.In a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2022
Entry Details
US Patent