BDBM666434 468::US20240116946, Example 467::US20240116946, Example 468

SMILES COc1ccc(Cl)c(c1)-c1cc2[nH]c(=O)n(-c3cncc4cccnc34)c(=O)c2s1

InChI Key InChIKey=QSKYCPYFYHFYTN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 666434   

TargetReplicase polyprotein 1a(2019-nCoV)
Gilead Sciences

US Patent
LigandPNGBDBM666434(US20240116946, Example 467 | US20240116946, Exampl...)
Affinity DataIC50: 2.54nMAssay Description:This biochemical assay measured small molecule inhibitor IC50 values against recombinant SARS-CoV-2 Main protease (Mpro). Compounds from 100 μM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Gilead Sciences

US Patent
LigandPNGBDBM666434(US20240116946, Example 467 | US20240116946, Exampl...)
Affinity DataIC50: 11.4nMAssay Description:This biochemical assay measured small molecule inhibitor IC50 values against recombinant SARS-CoV-2 Main protease (Mpro). Compounds from 100 μM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
US Patent