BDBM50430793 6-aza-PAT::CHEMBL2334756

SMILES CCNC(=O)Nc1ccc(cc1)-c1nc2C[C@@H]3CC[C@@H](N3C3COC3)c2c(n1)N1CCOC[C@@H]1C

InChI Key InChIKey=WLQPHPRJRBGPBN-XWFZLUIHSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50430793   

TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50430793(6-aza-PAT | CHEMBL2334756)
Affinity DataKi:  14nMAssay Description:Inhibition of human recombinant mTOR expressed in insect cells assessed as inhibition of phosphorylation of (GFP)-4-EBP1 protein after 30 mins by flu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50430793(6-aza-PAT | CHEMBL2334756)
Affinity DataIC50: >1.00E+4nMAssay Description:Time dependent inhibition of human CYP3A4 preincubated for 30 mins in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed