BDBM50006808 A-69412::CHEMBL292371::N-[1-(3-furyl)ethyl]-N-hydroxyurea

SMILES CC(N(O)C(N)=O)c1ccoc1

InChI Key InChIKey=PEYZZHBZAUNXCI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50006808   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50006808(A-69412 | CHEMBL292371 | N-[1-(3-furyl)ethyl]-N-hy...)
Affinity DataIC50:  1.10E+4nMAssay Description:The compound was tested for inhibitory activity against 5-Lipoxygenase in rat RBL-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006808(A-69412 | CHEMBL292371 | N-[1-(3-furyl)ethyl]-N-hy...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of 5-lipoxygenase (5-LO) measured as LTB4 production in human whole blood stimulated with calcium ionophore (A23187).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50006808(A-69412 | CHEMBL292371 | N-[1-(3-furyl)ethyl]-N-hy...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of 5-lipoxygenase on rat basophil leukemia cell line lysate (RBL-1 2H3 subline) by measuring 5-HETE productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed