BDBM50212239 5-(4-chlorophenyl)-N-(3,5-dimethoxyphenyl)furan-2-carboxamide::A-803467::CHEMBL250699
SMILES COc1cc(NC(=O)c2ccc(o2)-c2ccc(Cl)cc2)cc(OC)c1
InChI Key InChIKey=VHKBTPQDHDSBSP-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 75 hits for monomerid = 50212239
Affinity DataIC50: 6.74E+3nMAssay Description:Inhibition of inactivated human Nav1.7 sodium channelMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H](-)CGP-12177 from adrenergic beta2 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 1.18E+4nMAssay Description:Inhibition of human Nav1.3 channel expressed in HEK293 cells at -120 mV by patch clamp methodMore data for this Ligand-Target Pair
Affinity DataIC50: 79nMAssay Description:Inhibition of human Nav1.8 channel expressed in HEK293 cells at -100 mV by patch clamp methodMore data for this Ligand-Target Pair
Affinity DataIC50: 140nMAssay Description:Inhibition of Nav1.8 channel in rat dorsal root ganglion neurons assessed as blockade of TTX-R current by patch clamp methodMore data for this Ligand-Target Pair
Affinity DataIC50: 45nMAssay Description:Inhibition of recombinant rat Nav1.8 sodium channel assessed as blockade of TTXR current by patch clamp methodMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of human Nav1.8 channel expressed in HEK293 cells at -40 mV by patch clamp methodMore data for this Ligand-Target Pair
Affinity DataIC50: 9.49E+3nMAssay Description:Inhibition of human Nav1.2 channel expressed in HEK293 cells at -120 mV by patch clamp methodMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]DADLE from opioid delta receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 7.34E+3nMAssay Description:Inhibition of human Nav1.5 channel expressed in HEK293 cells at -90 mV by patch clamp methodMore data for this Ligand-Target Pair
Affinity DataIC50: 6.74E+3nMAssay Description:Inhibition of human Nav1.7 channel expressed in HEK293 cells at -60 mV by patch clamp methodMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of P2X2 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 7.18E+3nMAssay Description:Inhibition of inactivated human Nav1.2 sodium channelMore data for this Ligand-Target Pair
Affinity DataIC50: 7.44E+3nMAssay Description:Inhibition of inactivated human Nav1.5 sodium channelMore data for this Ligand-Target Pair
Affinity DataIC50: 2.45E+3nMAssay Description:Inhibition of inactivated human Nav1.3 sodium channelMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of inactivated human Nav1.8 sodium channelMore data for this Ligand-Target Pair
Affinity DataIC50: 125nMAssay Description:Inhibition of tetrodotoxin-resistant NaV1.8 in rat DRG neuron by electrophysiologyMore data for this Ligand-Target Pair
Affinity DataIC50: 850nMAssay Description:Inhibition of mouse NaV1.8 expressed in HEK293 cells by isotopic efflux assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of human recombinant NaV1.2 by electrophysiologyMore data for this Ligand-Target Pair
Affinity DataIC50: 140nMAssay Description:Inhibition of tetrodotoxin-resistant NaV1.8 in rat dorsal root ganglion neurons at holding potential -100 mV by whole-cell patch clamp electrophysiol...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of human recombinant NaV1.8 expressed in HEK293 cells by conventional voltageclamp electrophysiology assayMore data for this Ligand-Target Pair
Affinity DataIC50: 850nMAssay Description:Inhibition of mouse recombinant Nav 1.8 channel expressed in HEK293 cells by isotopic efflux assayMore data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+3nMAssay Description:Binding affinity to 5HT2A receptorMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of hERG potassium channel expressed in CHO cells by isotope efflux assayMore data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+3nMAssay Description:Binding affinity to CCKARMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of human recombinant Nav 1.8 channel expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+3nMAssay Description:Binding affinity to dopamine D1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+3nMAssay Description:Inhibition of human Nav1.5 channel at 1 uMMore data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+3nMAssay Description:Binding affinity to peripheral benzodiazepine receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 3.53E+4nMAssay Description:Inhibition of human Nav1.7 channel expressed in HEK293 cells at -120 mV by patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 3(Human)
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of KCNQ3 channelMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of human Nav1.8 channel expressed in human HEK293 cells by patch clamp methodMore data for this Ligand-Target Pair
Affinity DataIC50: 7.38E+3nMAssay Description:Inhibition of human Nav1.2 channel expressed in HEK293 cells at -60 mV by patch clamp methodMore data for this Ligand-Target Pair
Affinity DataIC50: 2.45E+3nMAssay Description:Inhibition of human Nav1.3 channel expressed in HEK293 cells at -60 mV by patch clamp methodMore data for this Ligand-Target Pair
Affinity DataIC50: 3.28E+4nMAssay Description:Inhibition of human Nav1.5 channel expressed in HEK293 cells at -150 mV by patch clamp methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Nav1.8 channel in rat dorsal root ganglion neurons assessed as blockade of TTX-R current by patch clamp methodMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]DPCPX from adenosine A1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+4nMAssay Description:Displacement of [125I]AB-MECA from adenosine A3 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]RX821002 from adrenergic alpha-2 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I]endothelin-1 from endothelin ETA receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 7.00E+3nMAssay Description:Displacement of [3H]SCH-23390 from dopamine D1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]Win 55212-2 from cannabinoid CB2 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]spiperone from dopamine D2 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]SCH23390 from dopamine D5 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I]MIP1-alpha from CCR1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I]APT from histamine H2 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]pirezepine from muscarinic M1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]AF-DX384 from muscarinic M2 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]4DAMP from muscarinic M4 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]4DAMP from muscarinic M5 receptorMore data for this Ligand-Target Pair