BDBM701975 ACV-2-231::US12129248, Compound ACV-74

SMILES O=C(Cc1cnc(NC(=O)C(F)(F)c2ccccc2)s1)Nc1ccc(N2CCCC2)cc1

InChI Key InChIKey=KOZAWAGNYCBEFL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 701975   

TargetChromobox protein homolog 7(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM701975(ACV-2-231 | US12129248, Compound ACV-74)
Affinity DataIC50: 0.0720nMAssay Description:The protocol for the CBX7 Fluorescence Polarization assay is as follows: A standard FP buffer (20 mM Tris, 250 mM NaCl, 0.01% w/v Tween20) at pH 8.0 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2025
Entry Details
US Patent