BDBM50198221 ADS-100380::CHEMBL216885::N-hydroxy-5-(1-methyl-3-(trifluoromethyl)-1H-pyrazol-5-yl)thiophene-2-carboxamide

SMILES Cn1nc(cc1-c1ccc(s1)C(=O)NO)C(F)(F)F

InChI Key InChIKey=CBAUPWKIZUBNOQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50198221   

TargetHistone deacetylase 1(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50198221(ADS-100380 | N-hydroxy-5-(1-methyl-3-(trifluoromet...)
Affinity DataIC50: 750nMAssay Description:Inhibition of HDAC activity measured by HDAC Fluorescent Activity Assay (mean of two experiments)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50198221(ADS-100380 | N-hydroxy-5-(1-methyl-3-(trifluoromet...)
Affinity DataIC50: 750nMAssay Description:Inhibition of HDAC activity measured by HDAC Fluorescent Activity Assay (mean of two experiments)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed