BDBM50241504 3-hydroxy-6-methyl-4-oxo-4H-pyran-2-carboxylic acid (biphenyl-4-ylmethyl)-amide::AM-2::CHEMBL255374::N-(biphenyl-4-ylmethyl)-3-hydroxy-6-methyl-4-oxo-4H-pyran-2-carboxamide

SMILES Cc1cc(=O)c(O)c(o1)C(=O)NCc1ccc(cc1)-c1ccccc1

InChI Key InChIKey=ZSZOBVLJWIXXND-UHFFFAOYSA-N

Data  13 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50241504   

TargetNeutrophil collagenase(Human)
Government College Women University

Curated by ChEMBL
LigandPNGBDBM50241504(AM-2 | CHEMBL255374 | N-(biphenyl-4-ylmethyl)-3-hy...)
Affinity DataIC50: 18nMAssay Description:Inhibition of human MMP-8More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMacrophage metalloelastase(Human)
Government College Women University

Curated by ChEMBL
LigandPNGBDBM50241504(AM-2 | CHEMBL255374 | N-(biphenyl-4-ylmethyl)-3-hy...)
Affinity DataIC50: 18nMAssay Description:Inhibition of human MMP-12More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetStromelysin-1(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50241504(AM-2 | CHEMBL255374 | N-(biphenyl-4-ylmethyl)-3-hy...)
Affinity DataIC50: 240nMAssay Description:Inhibition of human MMP3 catalytic domain by fluorescent substrate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetStromelysin-1(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50241504(AM-2 | CHEMBL255374 | N-(biphenyl-4-ylmethyl)-3-hy...)
Affinity DataIC50: 240nMAssay Description:Inhibition assay using matrix metalloproteinases.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2011
Entry Details Article
PubMed
TargetStromelysin-1(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50241504(AM-2 | CHEMBL255374 | N-(biphenyl-4-ylmethyl)-3-hy...)
Affinity DataIC50: 240nMAssay Description:Inhibition of human MMP-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
Target72 kDa type IV collagenase(Human)
Adamas University

Curated by ChEMBL
LigandPNGBDBM50241504(AM-2 | CHEMBL255374 | N-(biphenyl-4-ylmethyl)-3-hy...)
Affinity DataIC50: 610nMAssay Description:Inhibition of MMP2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetCollagenase 3(Human)
Government College Women University

Curated by ChEMBL
LigandPNGBDBM50241504(AM-2 | CHEMBL255374 | N-(biphenyl-4-ylmethyl)-3-hy...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human MMP-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
Target72 kDa type IV collagenase(Human)
Adamas University

Curated by ChEMBL
LigandPNGBDBM50241504(AM-2 | CHEMBL255374 | N-(biphenyl-4-ylmethyl)-3-hy...)
Affinity DataIC50: 9.30E+3nMAssay Description:Inhibition of human MMP2 catalytic domain by fluorescent substrate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Adamas University

Curated by ChEMBL
LigandPNGBDBM50241504(AM-2 | CHEMBL255374 | N-(biphenyl-4-ylmethyl)-3-hy...)
Affinity DataIC50: 9.30E+3nMAssay Description:Inhibition assay using matrix metalloproteinases.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2011
Entry Details Article
PubMed
TargetMatrilysin(Human)
Government College Women University

Curated by ChEMBL
LigandPNGBDBM50241504(AM-2 | CHEMBL255374 | N-(biphenyl-4-ylmethyl)-3-hy...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human MMP-7More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMatrix metalloproteinase-9(Human)
Government College Women University

Curated by ChEMBL
LigandPNGBDBM50241504(AM-2 | CHEMBL255374 | N-(biphenyl-4-ylmethyl)-3-hy...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human MMP-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetInterstitial collagenase(Human)
Government College Women University

Curated by ChEMBL
LigandPNGBDBM50241504(AM-2 | CHEMBL255374 | N-(biphenyl-4-ylmethyl)-3-hy...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human MMP-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetInterstitial collagenase(Human)
Government College Women University

Curated by ChEMBL
LigandPNGBDBM50241504(AM-2 | CHEMBL255374 | N-(biphenyl-4-ylmethyl)-3-hy...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human MMP1 catalytic domain by fluorescent substrate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed